There is inherent risk in drug discovery and development, and the stakes only become higher as your asset progresses. You need to be able to make decisions confidently at each phase of development to facilitate hand-offs to keep keep your program on track.
As a company of scientists engaged in cellular and molecular research ourselves, we understand the importance of the quality of the tools, reagents, and services you use to move a drug discovery or development project ahead. It’s critical to the accuracy of your results, and critical to achieving those results faster. When you work with CST, you can be confident that you’re generating accurate, reliable results and reducing risk as you move your project to the next phase.
Assay Platform Compatibility: Rest assured that your CST® products will perform on your systems, because we don’t limit them for use on specific platforms. Optimizing products to work on popular assay platforms makes it even easier to get your assays up and running quickly.
Industry-Leading Validation and Reproducibility: Your assay is only as good as your antibody is specific. Every one of our antibodies undergoes stringent, application-independent validation in-house to ensure that your assay won’t fail due to poor-performing antibodies.
Continuous, Long-Term Supply: You won’t need to be concerned about supply disruptions when you use CST products. More than 99% of CST products are available for immediate shipment to anywhere in the world because we make nearly everything we sell. For maximum peace of mind, you can also reserve a lot for the duration of your entire project.
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| Flexible, highly specific antibodies are essential to develop accurate and reproducible assays. Find the right CST ELISA kits and antibodies to meet your long-term immunoassay needs. | Ready-to-Ship ELISA Kits | Matched Antibody Pairs ELISA-Validated Antibodies Custom Labeling Services Ready-to-Ship Antibody Conjugates PTM Motif Antibodies Ready-to-Ship ELISA Kits |
Ready-to-Ship ELISA Kits |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| For antibodies you can trust to work consistently on your HCI instrument, CST offers a breadth of highly specific, IF-/HCA- (high content analysis) validated antibodies. | IF/HCA-Validated Antibodies | HCS-Validated Antibodies IF-ICC-Validated Antibody Conjugates |
HCI-Validated Antibodies |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| Save valuable time with antibodies validated and optimized for Simple Western systems. We’ve done the work to ensure specificity and the the ideal dilution factor. | Simple Western-Validated Antibodies | Simple Western-Validated Antibodies |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| Formalin-fixed, paraffin-embedded (FFPE) tissues are complex environments and can challenge the specificity of many antibodies. Find over 1,000 rigorously validated, recombinant monoclonal antibodies for IHC guaranteed to work in FFPE samples. | IHC-Validated Antibodies IHC-Validated Antibody Conjugates Biomarker Detection |
IHC-Validated Antibodies | IHC-Validated Antibodies IHC-Validated Antibody Conjugates |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| From low-to-high multiplex target detection, you can find a diverse portfolio of easy-to-use, flexible, and validated spatial biology solutions that are specific to the number of targets you want to monitor. | SignalStar® Multiplex IHC IHC-Validated Antibody Conjugates Carrier-Free (BSA- and Azide-Free) Antibodies Custom Labeling Services |
SignalStar Multiplex IHC |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| LC-MS Proteomics can aid discovery teams in identifying and validating drug targets, uncovering critical biomarkers for pharmacology groups, and determining on- and off-target effects and the mechanism of action during the development process. | Biomarker Detection Mechanism of Action PTMScan® Post-Translational Modification Quantitation Kits |
On- & Off-Target Effects PTMScan Post-Translational Modification Quantitation Kits |
On- & Off-Target Effects |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| Specificity and an optimal signal-to-noise ratio (S/N) for both conjugated and unconjugated antibodies is crucial for robust flow assays. Find CST flow-validated antibodies that have all undergone rigorous testing in biologically relevant models. | Flow-Validated Antibody Conjugates Flow Cytometry Panel Builder |
Flow-Validated Antibody Conjugates T Cell Activation Kits Flow Cytometry Panel Builder |
Flow-Validated Antibody Conjugates Flow Cytometry Panels Flow Cytometry Panel Builder |
| Target ID and Validation | Screening, Lead ID, and Optimization |
Preclinical Safety and Validation | |
|---|---|---|---|
| With a single experiment, identify signaling pathways and reveal molecular mechanisms in disease development. InTraSeq™ (Intracellular protein and Transcriptomic Sequencing) technology enables unbiased quantitation of mRNA expression alongside intracellular and cell surface proteins at the single-cell level. | InTraSeq™ Single Cell Analysis |
Scientists at CST have spent decades developing a deep knowledge of the biology, targets, and workflows most relevant to therapeutic research. We understand how crucial it is to get trustworthy results that will keep your project moving forward. Our ever-growing list of top-quality products and services helps drug discovery and development scientists identify key biomarkers and efficacy readouts as they work to discover novel treatments for diseases in many fields. Click an icon below to learn more.
The success or failure of any assay development exercise often hinges on how well an antibody performs on your detection platform. We maintain unmatched quality control by making nearly everything we sell and validating 100% of our antibodies in house. Platform-ready antibodies from CST are ideal for use on many of the most prevalent discovery platforms.
| Application | Platforms and Technologies | Solutions |
|---|---|---|
| High-Throughput ELISA/Immunoassay | Revvity AlphaLISA & AlphaScreen Revvity HTRF & LANCE TR-FRET MSD Instruments Luminex xMAP Quanterix SIMOA |
Ready-to-Ship Antibody Conjugates (Fluorescent Dyes, Biotin, Europium Cryptate) |
| Simple Western | Jess Automated Western Blot System Leo System |
Simple Western-Validated Antibodies |
| Spatial Biology | SignalStar Multiplex IHC Leica Microsystems Cell DIVE Lunaphore COMET Akoya Phenocycler 10x Genomics Visium Canopy CellScape NanoString GeoMx & CosMx Standard BioTools Hyperion |
SignalStar Multiplex IHC Panel Builder Ready-to-Ship Antibody Conjugates |
| High Content Analysis | Revvity Operetta Agilent Cytation Molecular Devices ImageXpress Yokogawa CellVoyager Araceli Endeavor |
|
| Flow Cytometry | Standard BioTools CyTOF Flow Cytometry Platforms Spectral Flow Cytometry |
Ready-to-Ship Antibody Conjugates |
With a comprehensive suite of best-in-class products, along with custom services meticulously tailored to meet your specific needs, CST is your best choice for getting reliable results fast. From custom conjugation guaranteed to meet your requirements to antibody formulations optimized for your platform, you can count on CST to deliver precisely what you need—when you need it.
| Product Type | Applications |
|---|---|
| Conjugated Antibodies |
IF/High Content Analysis Flow Cytometry Immunohistochemistry Spatial Biology Immunoassays |
| Non-Conjugated Antibodies |
IF/High Content Analysis Simple Western Immunohistochemistry Flow Cytometry |
| Immunoassay Tools |
Matched Antibody Pairs ELISA-Validated Antibodies ELISA Kits (96-Well, 384-Well) Carrier-Free Antibodies Custom Labeling Services |
| Product Type | Applications |
|---|---|
| PTMScan Post-Translational Modification Quantitation Kits | Assess low-abundance post-translational modifications by LC-MS |
| SignalStar Multiplex IHC kits | Spatial Biology |
| InTraSeq Single Cell Analysis Kits | Single-Cell Analysis |
| ELISA Kits | Pair-Based Immunoassay |
| Cellular Assay Kits | Cell Death, T-Cell Activation, Senescence, and More |
| Service Type | Applications |
|---|---|
| Custom Labeling Services | Conjugate antibodies to fluorescent dyes, biotin/haptens, europium, beads, or enzymes for your specific assay |
| Proteomics Analytical Services |
Post-Translational Modifications Global Proteome Profiling Biomarker Detection Mechanism of Action (MOA) On- & Off-Target Effects |
| Bulk Orders and Lot Reservations |
Order products in bulk Reserve a lot for the duration of your project |
